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New Age Medspa · Anchorage, Alaska

Ariessence
Pure PDGF+

Pharmaceutical-grade skin renewal

The most potent growth factor in regenerative aesthetics — sterile, consistent, and clinically proven. No blood draw. No guesswork. Just science that signals your skin to rebuild from within.

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300K× More growth factors
than PRP
4 FDA-approved
medical uses
5M+ Patients treated
with PDGF products
0 Blood draw
required
What is pure PDGF+

Your skin already knows how to heal. PDGF+ tells it to do it better.

Platelet-Derived Growth Factor (PDGF) is one of the body's most conserved and well-studied proteins for tissue repair. It works by binding to receptors on fibroblast cells — the cells responsible for producing collagen and elastin — and signaling them to activate, proliferate, and rebuild.

Ariessence Pure PDGF+ is a laboratory-engineered, recombinant version of this protein. It is pharmaceutical-grade, sterile, and precisely formulated — meaning every application delivers the exact same concentration of growth factor, every time. No variables. No blood draw. No reliance on your platelet count that day.

Four clean ingredients. Nothing else.
Water
Sterile base carrier
Sodium Acetate
Stabilizing buffer — maintains pH integrity
Hyaluronic Acid
Deep hydration and barrier restoration
SH-Polypeptide-59 Dimer
The active growth factor — signals collagen and elastin production

No human or animal DNA. No mRNA. No foreign biological material of any kind.

15 yrs
PDGF has been used clinically for over 15 years with an established safety record across millions of patients.
How we use it

Three powerful ways PDGF+ is used at New Age Medspa

PDGF+ isn't a standalone facial — it's a precision amplifier. It works in combination with the treatments that open, activate, or challenge the skin, making those procedures significantly more effective.

Post-Microneedling Application

The most powerful pairing. Used after SkinPen or RF microneedling to supercharge results.

Micro-channels act as direct delivery pathways into the dermis
Growth factors reach 10–20× deeper than topical application alone
Amplifies collagen cascade already triggered by microneedling
Reduces redness and shortens recovery time vs. microneedling alone
Compatible with SkinPen, Potenza RF, and all needle-based treatments

Post-Laser & Resurfacing Add-On

Applied after LaseMD Ultra, chemical peels, or any resurfacing treatment that disrupts the skin barrier.

Calms inflammation and accelerates tissue repair after laser energy
Restores barrier function faster with hyaluronic acid + PDGF combination
Enhances pigmentation correction outcomes post-laser
Reduces risk of post-inflammatory response
Compatible with ZO 3-Step Peel, LaseMD Ultra, and chemical peels

Standalone Skin Renewal Treatment

For clients seeking a lower-downtime option — PDGF+ is applied to the clean skin surface for targeted cellular activation.

Ideal for maintenance between more intensive treatments
Immediate hydration and glow from hyaluronic acid component
Collagen-stimulating benefits build gradually over 4–8 weeks
Zero downtime — wear makeup as normal within hours
Great for sensitive skin or clients new to growth factor therapy
Why it works

The science is settled. The results speak for themselves.

PDGF is one of the most researched growth factors in medicine — used in FDA-approved treatments for over 15 years. What makes Ariessence unique is the purity, concentration, and consistency of delivery.

Ariessence PDGF+
vs. PRP
Sterile · pharmaceutical-grade
Variable · blood-derived
300,000× growth factor concentration
Depends on your platelet count
No blood draw required
Venous blood draw + centrifuge
Consistent every single time
Results vary by person and session
No human/animal DNA or mRNA
Contains your blood components

Collagen & Elastin Stimulation

PDGF binds directly to fibroblast receptors — the cells that make collagen and elastin — signaling them to multiply and produce new structural proteins. The result is measurably firmer, smoother skin over 4–8 weeks as the new collagen matrix forms.

Visible in 4–8 weeks

Accelerated Healing & Reduced Downtime

Applied immediately after microneedling or laser resurfacing, PDGF+ enters the skin through open channels and actively calms the inflammatory response. Clients consistently experience less redness and faster recovery compared to treatment without it.

Same-day recovery support

Deep Hydration via Hyaluronic Acid

The PDGF+ formula is paired with hyaluronic acid — a molecule that holds up to 1,000 times its weight in water. This means your skin is deeply plumped and hydrated immediately, while the growth factor does its longer-term collagen work underneath.

Immediate glow

Long-Lasting Results

Because PDGF+ stimulates your skin's own collagen production — rather than adding a foreign substance — the results are structural and lasting. Improvement continues building for weeks and can be maintained for 6–12 months with a simple touch-up schedule.

Results last 6–12 months
Is it right for you

PDGF+ works for nearly everyone. Here's who benefits most.

Because it doesn't rely on heat, light, or aggressive chemistry, PDGF+ is one of the most inclusive skin treatments available — safe for all skin tones and types.

Fine lines and early signs of aging
Acne scarring or textural irregularities
Dull, tired, or dehydrated skin
Enlarged or visible pores
Uneven tone or mild hyperpigmentation
Anyone recovering from microneedling or laser
Those who want results without a blood draw
Darker skin tones sensitive to heat treatments
A few reasons to wait or discuss first
Pregnancy or breastfeeding — safety not yet studied in this population
Known allergy to hyaluronic acid or acetate buffers
Active skin infection or open wounds in the treatment area
Using aggressive exfoliants — wait 3–5 days post-peel before PDGF+ application
What to expect

Results that build over time

PDGF+ works with your biology — so results are gradual, natural-looking, and cumulative. Here's what a typical treatment journey looks like.

Day of treatment

Immediate glow + hydration

The hyaluronic acid in the formula works immediately — skin feels plumped, hydrated, and has a noticeable luminosity. Some mild redness from the microneedling (if combined) subsides within hours to a day.

Days 3–7

Smoother texture, improved tone

The cellular signaling from PDGF+ is already underway. Most clients notice their skin feels smoother and looks more even. Fine lines may appear subtly softened as hydration improves and early collagen activity begins.

Weeks 4–8

Collagen production peaks

This is when the real transformation becomes visible. New collagen fibers have had time to form and organize — skin is measurably firmer, pores appear smaller, and scarring looks less pronounced. This is the window where the most dramatic results appear.

Months 3–6

Results maintained — touch-up window

Results from a full series (2–4 treatments) can last 6–12 months. Most clients return for a maintenance session at the 6-month mark to sustain and build on their results. Each subsequent treatment compounds the benefits of the last.

PDGF+ is available as part of our monthly specials.

We regularly feature PDGF+ combinations — with SkinPen microneedling, LaseMD Ultra, and more — at special pricing. Check this month's offers to see what's available.

View This Month's Specials →
Your questions

Everything you want to know about PDGF+

Honest, thorough answers — because informed clients always get better results. Don't see your question? Call or text us directly.

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Platelet-Derived Growth Factor is a naturally occurring signaling protein your body uses to initiate tissue repair. When your skin is injured or stimulated, PDGF binds to receptors on fibroblast cells and tells them to activate, divide, and produce collagen and elastin. Ariessence Pure PDGF+ is a synthetic, recombinant version of this protein — produced in a laboratory with pharmaceutical precision, delivering the same signal your body already knows how to respond to, but at a far higher concentration than your body would generate naturally.
PRP (platelet-rich plasma) draws and processes your own blood to extract growth factors — but the concentration and potency vary based on your individual platelet count and the quality of processing. Exosomes are cell-derived vesicles containing multiple signaling compounds, but they carry sterility concerns and variable sourcing. Ariessence PDGF+ contains a single, precisely dosed, pharmaceutical-grade growth factor — with up to 300,000× the concentration of PRP — produced under controlled laboratory conditions. Same results, every time, without a blood draw.
PDGF has an excellent safety record built over 15+ years of clinical use and 5 million+ patients treated. It is FDA-approved as an active ingredient in four medical treatments — including wound-healing and bone regeneration applications. Ariessence Pure PDGF+ is used in aesthetic medicine as a cosmetic product — this is standard practice for many ingredients that have proven medical safety records. It contains no human or animal DNA, no mRNA, and no biological material beyond its four clean, listed ingredients. It is also free from the contamination risks associated with blood-derived products.
The PDGF+ application itself is completely painless — it's a topical serum. When combined with microneedling, we apply numbing cream beforehand so the needling portion is very well tolerated. Most clients describe it as mild pressure or a light scratching sensation. Immediately after, skin may feel tight and look flushed — this is normal and a sign of healthy healing activity. The hyaluronic acid in the PDGF+ formula leaves skin feeling immediately hydrated and refreshed.
Many clients notice meaningful improvement after a single session. For a complete transformation — especially for scarring, deeper lines, or significant textural concerns — we recommend a series of 2–4 treatments spaced 3–6 weeks apart. This spacing allows your skin's collagen cycle to respond fully between sessions. Maintenance treatments every 6–12 months sustain and build on your results over time.
As a standalone treatment, PDGF+ has essentially zero downtime. When combined with microneedling, expect 24–48 hours of mild redness — less than you'd experience from microneedling alone. Aftercare is simple: avoid washing your face for 12 hours, skip strenuous exercise or steam for 24 hours, use a gentle moisturizer, and always apply SPF when outdoors. You can wear makeup within a few hours for standalone application, or wait 24 hours after combined microneedling.
Yes — PDGF+ pairs well with most aesthetic treatments and can actually enhance healing after neuromodulators and filler. We typically time PDGF+ applications after neurotoxin injections have had time to settle (24–48 hours). Combined treatment plans are one of the most effective strategies for comprehensive rejuvenation, and our team will design a schedule that sequences your treatments for maximum benefit.
New Age Medspa is one of the only providers in Anchorage offering Ariessence Pure PDGF+ as part of a comprehensive regenerative skin program. Our team is led by Natasha Sherrill, FNP — a clinician who carefully selects every treatment in our menu based on evidence, not trends. We treat PDGF+ not as a gimmick, but as a clinical tool — pairing it strategically with our SkinPen microneedling, Potenza RF, LaseMD Ultra, and other resurfacing treatments for compounded results you can actually see.
Get started

Your skin's ability to rebuild is real.
We just give it the signal.

Whether you're new to growth factor therapy or ready to add PDGF+ to an existing treatment plan, we'll build a strategy that fits your skin, your timeline, and your goals.

Book a Consultation This Month's Specials
Anchorage's regenerative aesthetics specialists
Pharmaceutical-grade · sterile · consistent
Led by Natasha Sherrill, FNP
(907) 921-4281 · Anchorage, AK